International Blood Research & Reviews 2020-03-28T19:38:42+00:00 International Blood Research & Reviews Open Journal Systems <p style="text-align: justify;"><strong>International Blood Research &amp; Reviews (ISSN:&nbsp;2321–7219)</strong> aims to publish high quality papers (<a href="/index.php/IBRR/general-guideline-for-authors">Click here for Types of paper</a>) in all areas of ‘Blood related research’. The journal also encourages the submission of useful reports of negative results. This is a quality controlled,&nbsp;OPEN&nbsp;peer reviewed, open access INTERNATIONAL journal.</p> Kell Blood Group Antigens Not Found in Indigenes of Ogoni Ethnic Group of Rivers State, Nigeria 2020-03-28T19:38:42+00:00 Serekara Gideon Christian Evelyn Mgbeoma Eze Anthony Chijioke Uzoanya Ezimah Fiekumo Igbida Buseri <p><strong>Aim: </strong>The aim of the study was to determine the frequency of occurrence and percentage distribution of Kell blood group antigens in indigenes of Ogoni ethnic group of Rivers State, Nigeria.</p> <p><strong>Study Design:</strong>&nbsp; This was a cross-sectional study carried out among indigenes of Ogoni whose first generational parental origin is Ogoni. A total of 101 subjects (49 females and 52 males), within the age of 30–60 years were recruited for the study and they were apparently healthy and free from transfusion transmissible infections upon serological screening.</p> <p><strong>Place and Duration of Study:</strong> Ogoniland is located in an area along the Niger Delta Eastern edge, and to the north-east of the Imo River and Port Harcourt city. Ogoniland covers about 1036 Sq Km and borders the Bay of Guinea. All participants were recruited in Bori. Bori is the traditional headquarter of Ogoni. Bori is located on latitude: 4<sup>0</sup>40ʹ34.64ʺ N and longitude: 7<sup>0</sup>21ʹ54.68ʺ E. The analysis was carried out at the Post Graduate Laboratory of Rivers State University, Nkpolu-Oroworukwo, Port Harcourt, Rivers State, Nigeria. Port Harcourt, the capital of Rivers State, is located on latitude 4.75<sup>0</sup>N and longitude 7.00<sup>0</sup>E and lies along Bonny River in the Niger Delta. All subjects were recruited the same day and their blood samples collected on 2<sup>nd</sup> October, 2019, and analysis conducted on 3<sup>rd</sup> October, 2019.</p> <p><strong>Methodology:</strong> Identification of Kell blood group antigens was done using Anti-Kell monoclonal reagent, prepared by Lorne Laboratories Ltd, UK. Lot No: 76090-A5; Expiry Date: 2021/02/21. Phenotyping of red cells was done using tube method as described by Lorne Laboratory Ltd.</p> <p><strong>Results:</strong> The result showed zero frequency of occurrence and percentage distribution of Kell blood group antigen in the studied population (49 males and 52 females).</p> <p><strong>Conclusion:</strong> The presence of Kell blood group antigens in indigenes of Ogoni recruited for the study which serve as representative of the Ogonis was rare. It is therefore necessary to take into cognizance that haemolytic transfusion reactions due to Kell antigens and antibodies will rarely occur, and as such Kell blood group is not significant in blood transfusion and in antenatal and blood group serology amongst the Ogonis.</p> 2020-03-04T00:00:00+00:00 ##submission.copyrightStatement## Distribution of ABO, Rhesus D and Subgroups of ABO among Blood Donors in Sokoto, North Western Nigeria 2020-03-28T19:38:41+00:00 A. B. Ibrahim H. Attahiru O. Erhabor P. F. Udomah A. Yakubu H. A. Buhari H. M. Ahmed F. U. Onuigwe D. Isah M. U. Kalgo U. Abubakar <p>ABO, Rhesus D and&nbsp;subgroups of ABO are highly immunogenic and are the common cause of antibody production in mismatched blood transfusions, haemolytic transfusion reaction and maternal alloimmunization. The aim of this study was to determine the occurrence of ABO, Rh D and subgroups of ABO among blood donors attending Specialist Hospital Sokoto, Nigeria.&nbsp;ABO, Rhesus D and subgroups of ABO antigen status of 176 blood donors with mean age of 30.44 ± 8.210 years attending Specialist Hospital Sokoto were determined using tile method for ABO and Rh D and conventional tube method for anti- A1, anti- H reagents for ABO subgroups respectively. Among the 176 subjects tested, blood group O+ was the most frequent group with 93 (52.8%), 39 (22.2%) were blood group B+, 37(21.0%) were blood group A+, 5 (2.8%) were blood group AB+, 2 (1.1%) were blood group O-. No data was obtained for A-, B- and AB- blood groups.&nbsp; Out of 37 A blood groups obtained, 31 (83.8%) had A1 antigens and 6 (16.2%) had A2 antigens. Out of the 5 AB blood groups, all had A1B antigens. The study also shows that there was statistically significant difference between blood group A and ethnic groups (Hausa, Fulani and Yoruba) (p&lt;0.05). Blood group O was found to be the most frequent followed by B, A and AB except among Hausa which revealed a pattern of O&gt; A&gt; B&gt; AB. ABO, subgroups shows majority had A1 followed by A2 and A1B respectively.</p> 2020-03-04T00:00:00+00:00 ##submission.copyrightStatement##